Paraquat/Parkinson’s Disease??<BR>Cell Death and Differentiation (2010) 17:1115-1125 <BR>“The epidemiological and clinical evidence that PQ may favor the onset of PD is inconclusive”. <BR>“In the case of PQ, the link between experiments in rodents and potential human adverse effects is weak.” <BR> <BR>PLoS ONE (2016) 11(10):e0164094 <BR>“Paraquat administered maximum tolerated doses did not induce any neuro-pathogenic effects.” <BR> <BR>2019 EPA-OPP Review (June 26, 2019) <BR>Data from 28 human, 217 animal, and 244 in vitro studies <BR>“Weight of evidence was insufficient to link paraquat exposure from pesticide use of US registered products to PD in humans.” <BR> <BR>Journal of Toxicology and Environmental Health (2019) 22(5-6):172-302 <BR>Data indicates a positive association between exposure to PQ and PD occurrence, but the weight of evidence does not enable one to assume an indisputable cause/effect relationship.” <BR> <BR>Environmental Research (2020) 191:110186*** <BR>Hazard ratio for ever-use of paraquat was elevated but not statistically significant.” <BR> <BR>Journal of Occupational Medicine and Toxicology (2021) 16-21 <BR>“No evidence of increased risk of PD or increased mortality from other causes among PQ production workers whose exposure to PQ on a daily basis was at least comparable to that of PQ sprayer or mixer/loader.”  <BR> <BR>Neurotoxicology (2021) 86:80-184 <BR>“A consensus exists in the scientific community that the available evidence does not warrant a claim that paraquat causes Parkinson’s disease.” <BR> <BR>Handbook of Neurotoxicity (2021) 1-19 <BR>“Weight of evidence is sufficient to conclude a generic association between PQ exposure and PD exists, but is not sufficient to conclude that this is a causal relationship.”<BR>