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TITLE
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Herbicide Modes of Action
AUTHOR
Eric P. Prostko
Extension Weed Specialist
Department of Crop and Soil Sciences
The University of Georgia
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TABLE OF CONTENTS
Herbicide Modes of Action
Some things to remember...
Mode of Action
Mechanism of Action (Site)
ACCase Inhibitors
Rotted meristem
ALS Inhibitors
Commonly Used ALS Herbicides
Cadre 'yellow flash'; Staple+ on Sorghum
Resolve 25WG (rimsulfuron) Injury to Field Corn
Photosystem II Inhibitors
Bladex; Cotoran
Photosystem I Inhibitors
Paraquat
PPO Inhibiting Herbicides
Blazer Injury on Peanut; Valor Injury on Peanut; Cobra on Soybeans
Carotenoid Biosynthesis Inhibitors
Command; Zorial; Laudis
EPSP Synthase Inhibitor
Injury
Glutamine Synthetase Inhibitors
Injury
Mitosis Inhibitors
Prowl Injury on Corn
Dual Injury
Fatty Acid and Lipid Biosynthesis Inhibitors
Injury
Synthetic Auxins
Injury
Unknown MOA
MSMA on Peanut and Zoysia
UGA Weed Science
SLIDE CONTENTS
Herbicide Modes of Action Eric P. Prostko Extension Weed Specialist Department of Crop & Soil Sciences The University of Georgia April 2008
Some things to remember…. photosynthesis (food) respiration (energy) amino acids (proteins/growth) lipids (cell membranes) pigments (energy/light capture) chlorophyll, carotenoids mitosis (cell division)
Mode of Action the sequence of events that leads to plant death or growth interruption 2 phases * movement to target site * interaction at target site
Mechanism of Action (Site) Location at which a herbicide exerts its toxicity at the cellular level more specific
ACCase Inhibitors Inhibit acetyl-CoA-carboxylase (ACCase) enzyme Enzyme needed for fatty acid synthesis Dim’s and Fop’s Achieve, Assure, Axial, Fusilade, Poast, Select
Source: W. K. Vencill, UGA “rotted” meristem
ALS Inhibitors Inhibit acetolactate synthase (ALS) enzyme enzyme needed to produce certain amino acids (isoleucine, leucine, valine)
Commonly Used ALS Herbicides Accent Ally/Cimarron Beacon Beyond Cadre Classic Envoke Exceed Express Finesse FirstRate Glean Harmony Extra Maverick Pro Osprey Peak Permit Pursuit Python Scepter Staple Strongarm
Cadre “yellow flash” Staple+ on Sorghum
Resolve 25WG (rimsulfuron) Injury to Field Corn Pictures @ 18 DAT 1.0 oz/A Applied PRE
Photosystem II Inhibitors Inhibit photosynthesis by binding to QB-binding niche on D1 protein Evik, Caparol, Atrazine, Basagran, Buctril, Direx, Cotoron, Lorox, Sencor, Simazine
Bladex Cotoran Source: W. K. Vencill, UGA
Photosystem I Inhibitors Accept electrons from PSI to form radicals Super radicals formed to create peroxides Diquat, paraquat
Paraquat Source: Purdue University
PPO Inhibiting Herbicides PPO or Protox Protoporphyrinogen oxidase Enzyme found in chloroplast and mitochondria needed for formation of chlorophyll Cell membrane destruction Many common herbicides have this mode of action!! Ultra Blazer, Cobra, Goal, Reflex, Ronstar, Resource, Aim, Valor, Storm, Spartan, ET
Blazer Injury on Peanut Valor Injury on Peanut Cobra on Soybeans
Carotenoid Biosynthesis Inhibitors Inhibit phytoene desaturase (PDS) or hydroxyphenyl pyruvate dioxygenase (HPPD) Command, Callisto, Laudis, Solicam/Zorial, Impact
Command Zorial Laudis
EPSP Synthase Inhibitor EPSP synthase needed for production of certain amino acids (tryptophan, tyrosine, and phenylalanine) glyphosate
Source: Purdue University Weed Science Source: MSU Weed Science
Glutamine Synthetase Inhibitors Glutamine synthetase converts glutamate and ammonia to glutamine Causes ammonia accumulation in plants Liberty, Ignite
Source: University of Missouri Weed Science
Mitosis Inhibitors Microtubule inhibition Treflan, Prowl, Sonalan, Surflan, Dacthal Inhibition of very long-chain fatty acids Dual Magnum, Outlook, Intrro
Prowl Injury on Corn
Source: University of Wisconsin Weed Science Dual Injury
Fatty Acid and Lipid Biosynthesis Inhibitors Inhibition of lipid synthesis (not ACCase) Prefar, Sutan, Eptam, Eradicane, Ordram, Tillam, Bolero
Source: Purdue University Weed Science Source: UC-Davis Weed Science
Synthetic Auxins Disrupt hormonal balance 2,4-D, Banvel, Clarity, Status, Stinger, MCPA, Facet, Remedy, Grazon P+D
Source: Purdue University Weed Science Source: Purdue University Weed Science
Unknown MOA DSMA, MSMA Cell membrane destruction???
MSMA on Peanut MSMA on Zoysia
UGA Weed Science www.gaweed.com